A recent article by Azo Materials featured a microfluidic nanoparticle analyser product from Spectrodyne. The “nCS1” system appears to reap the benefits of precise small volume fluid manipulations in disposable microfluidic cartridges to eliminate sample cross-talk and any need for cleaning.
The system is an advanced Coulter counter, and has sufficiently high resolution to allow it to achieve superior measurements of particle polydispersity in a given sample. Particle sizing is from 40-2000 nm for 10^5 to 10^12 particles/mL, with precision of better than +/- 3% on sizing and +/-10% on concentration.