HJC Consulting Inc. has a broad base of technical expertise relating to analytical chemistry generally and microfluidics (also termed lab-on-a-chip) in particular.
Microfluidics Applications
- DNA amplification & sizing
- PCR-CE
- PCR-MPA
- continuous-flow PCR
- cell sorting
- biomolecule linkage chemistry
- disease diagnostics
- capillarity & Laplace pressure
- electrophoretic separations of DNA & other species
- sample gating
- field inversion
- chip cleaning & rejuvenation
- on-chip fluorescence & electrochemical detection
Microfabrication & Chip Design
- chip architecture
- sample input & waste
- wet or dry reagent storage on-chip
- pumping & valving
- metering & mixing
- filtration
- heating
- CAD design
- FEA modelling
- glass, silicon, SU-8 microfabrication
- polymer microfabrication
- injection moulding, lamination, and hot embossing processes
- thermoplastics (PMMA, PC, …)
- elastomers (limited)
- connections with prototyping houses, small & larger fab houses
Analytical Separations
- CE: capillary electrophoresis
- oil-field anion & cation analysis
- CGE: capillary gel electrophoresis
- DNA sequencing
- MECC/MEKC: micellar electrokinetic capillary chromatography
Other Bioapplications
- DNA sequencing
- metabolomics
- cannabinoid analysis
- ELISA-based sensing
- glucose sensing
- industrial process water analysis
Instrumentation
- detection
- on-chip fluorescence (LIF, DIF)
- on-capillary fluorescence, indirect fluorescence, UV absorbance
- electrochemical
- MOF-filtres
- electronics (with collaborators)
- instrument control, I/O synchronisation
- SW/FW
- high voltage
- Peltier temperature control
- pressurised liquid/gas phase sample extraction
- pumping & pulse dampening
- peristaltic, syringe, etc.
- industrial design (with collaborators)
Data Analysis
- statistical analysis
- data smoothing
- peak quantitation, LoD, sensitivity
- multivariate analysis
Please email us for more information about scientific competences.